One of the biggest complaints with Fallout 4, perhaps the only complaint, is the poor optimization for PC. Well the good news is an audacious and well known modder named “Bilago” has released a configuration tool to help things run better on your rig. Most options are self explanatory and let you adjust things like frame cap, Kodix’s FPS boost(which may not work on all PCs), world and first person FOV, and various other standard tweaks. I want to also mention here that if you uncap your framerate it is highly recommended to turn on Vsync for the game in your video card’s control panel(ATI Catalyst/NVidia Control Panel) .
You can grab the configuration tool here.